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Person with cancer—lung cancer molecular pathology test results, code N[N]

Definition

The results of a molecular pathology test for genetic and molecular abnormalities in a person with cancer, as represented by a code.

Components

Data Element (this item)
Person with cancer—lung cancer molecular pathology test results, code N[N]

Representation

This representation is based on the value domain for this data element, more information is available at " Lung cancer molecular pathology test results code N[N] ".
Data Type Number
Format N[N]
Maximum character length 2
Values
Value Meaning Start Date End Date
Permissible Values 1 APC - adenomatous polyposis coli
2 ATM - ataxia telangiectasia mutated
3 EGFR - epidermal growth factor receptor
4 ERBB4 - v-erb-a erythroblastic leukaemia viral oncogene homolog 4
5 ERCC1 - excision repair cross-complementing rodent repair deficiency, complementation group 1
6 KDR - kinase insert domain receptor
7 KRAS - v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
8 NF1 - neurofibromin 1
9 PTEN - phosphatase and tensin homolog
10 RB1 - retinoblastoma 1
11 RRM1 - ribonucleotide reductase M1
12 STK11 - serine/threonine kinase 11
13 TYMS - thymidylate synthetase
14 P53 - tumour protein p53
15 ERBB2 - v-erb-a erythroblastic leukaemia viral oncogene homolog 2
16 EML4-ALK - echinoderm microtubule-associated protein-like 4 – anaplastic lymphoma kinase
17 B-RAF - v-Raf murine sarcoma viral oncogene homolog B1
18 ROS - C-Ros Oncogene 1, Receptor Tyrosine Kinase
19 MET - Met Proto-Oncogene (Hepatocyte Growth Factor Receptor)
88 Other
Supplementary Values 97 Not applicable-no abnormalities detected
98 Unknown whether abnormalities detected
99 Abnormalities detected but type not stated/inadequately described

Comments

Guide for use:

Record the results of a molecular pathology test for genetic and molecular abnormalities in a person with cancer.

This item should be completed when the data element Molecular pathology indicator is coded as 1, denoting that molecular testing has been performed.

Molecular testing is usually performed when the result may influence treatment. For example, somatic mutations in the EGFR gene are associated with favourable outcomes from treatment with gefitinib.

Comments:
The presence of genetic or molecular abnormalities may be of clinical significance and influence treatment decisions.

References

Harris TJR & McCormick F 2010. The molecular pathology of cancer. Nat. Rev. Clin. Oncol. 7:251-265


This content Based on Australian Institute of Health and Welfare material. Attribution provided as required under the AIHW CC-BY licence.

Related content

Relation Count
Input in Derivations 0
Output in Derivations 0
Inclusion in Data Set Specifications 1
Inclusion in Data Distributions 0
As a numerator in an Indicator 0
As a denominator in an Indicator 0
As a disaggregation in an Indicator 0