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Lung cancer molecular pathology test results code N[N]

Definition

A code set representing the genetic or molecular abnormalities detected in lung cancer molecular pathology testing.

Representation

Data Type Number
Format N[N]
Maximum character length 2

Values

Value Meaning Start Date End Date
Permissible Values 1 APC - adenomatous polyposis coli
2 ATM - ataxia telangiectasia mutated
3 EGFR - epidermal growth factor receptor
4 ERBB4 - v-erb-a erythroblastic leukaemia viral oncogene homolog 4
5 ERCC1 - excision repair cross-complementing rodent repair deficiency, complementation group 1
6 KDR - kinase insert domain receptor
7 KRAS - v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
8 NF1 - neurofibromin 1
9 PTEN - phosphatase and tensin homolog
10 RB1 - retinoblastoma 1
11 RRM1 - ribonucleotide reductase M1
12 STK11 - serine/threonine kinase 11
13 TYMS - thymidylate synthetase
14 P53 - tumour protein p53
15 ERBB2 - v-erb-a erythroblastic leukaemia viral oncogene homolog 2
16 EML4-ALK - echinoderm microtubule-associated protein-like 4 – anaplastic lymphoma kinase
17 B-RAF - v-Raf murine sarcoma viral oncogene homolog B1
18 ROS - C-Ros Oncogene 1, Receptor Tyrosine Kinase
19 MET - Met Proto-Oncogene (Hepatocyte Growth Factor Receptor)
88 Other
Supplementary Values 97 Not applicable-no abnormalities detected
98 Unknown whether abnormalities detected
99 Abnormalities detected but type not stated/inadequately described

Comments

Guide for use:

Each code represents a HUGO Gene Nomenclature Committee (HGNC) assigned unique gene symbol. The full name, location and additional information about each gene can be obtained from their online database at www.genenames.org.

Record the code for each genetic or molecular abnormality detected.

Molecular pathology testing is usually performed for non-small cell lung cancer (NSCLC) and when the result may influence treatment.

References

Harris TJR & McCormick F 2010. The molecular pathology of cancer. Nat. Rev. Clin. Oncol. 7:251-265

Royal College of Pathologists of Australasia 2010. Lung cancer structured reporting protocol. 1st Edition (Version 1.0). Surry Hills, NSW: Royal College of Pathologists of Australasia

HGNC Database, HUGO Gene Nomenclature Committee (HGNC), EMBL Outstation - Hinxton, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1SD, UK. Viewed 21 June 2011, http://www.genenames.org
This content Based on Australian Institute of Health and Welfare material. Attribution provided as required under the AIHW CC-BY licence.

Related content

Relation Count
Data Elements implementing this Value Domain 1