Definition
Representation
Data Type | Number |
---|---|
Format | N[N] |
Maximum character length | 2 |
Values
Value | Meaning | Start Date | End Date | |
---|---|---|---|---|
Permissible Values | 1 | APC - adenomatous polyposis coli | ||
2 | ATM - ataxia telangiectasia mutated | |||
3 | EGFR - epidermal growth factor receptor | |||
4 | ERBB4 - v-erb-a erythroblastic leukaemia viral oncogene homolog 4 | |||
5 | ERCC1 - excision repair cross-complementing rodent repair deficiency, complementation group 1 | |||
6 | KDR - kinase insert domain receptor | |||
7 | KRAS - v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | |||
8 | NF1 - neurofibromin 1 | |||
9 | PTEN - phosphatase and tensin homolog | |||
10 | RB1 - retinoblastoma 1 | |||
11 | RRM1 - ribonucleotide reductase M1 | |||
12 | STK11 - serine/threonine kinase 11 | |||
13 | TYMS - thymidylate synthetase | |||
14 | P53 - tumour protein p53 | |||
15 | ERBB2 - v-erb-a erythroblastic leukaemia viral oncogene homolog 2 | |||
16 | EML4-ALK - echinoderm microtubule-associated protein-like 4 – anaplastic lymphoma kinase | |||
17 | B-RAF - v-Raf murine sarcoma viral oncogene homolog B1 | |||
18 | ROS - C-Ros Oncogene 1, Receptor Tyrosine Kinase | |||
19 | MET - Met Proto-Oncogene (Hepatocyte Growth Factor Receptor) | |||
88 | Other | |||
Supplementary Values | 97 | Not applicable-no abnormalities detected | ||
98 | Unknown whether abnormalities detected | |||
99 | Abnormalities detected but type not stated/inadequately described |
Comments
Guide for use:
Each code represents a HUGO Gene Nomenclature Committee (HGNC) assigned unique gene symbol. The full name, location and additional information about each gene can be obtained from their online database at www.genenames.org.
Record the code for each genetic or molecular abnormality detected.
Molecular pathology testing is usually performed for non-small cell lung cancer (NSCLC) and when the result may influence treatment.References
Harris TJR & McCormick F 2010. The molecular pathology of cancer. Nat. Rev. Clin. Oncol. 7:251-265
Royal College of Pathologists of Australasia 2010. Lung cancer structured reporting protocol. 1st Edition (Version 1.0). Surry Hills, NSW: Royal College of Pathologists of Australasia
HGNC Database, HUGO Gene Nomenclature Committee (HGNC), EMBL Outstation - Hinxton, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1SD, UK. Viewed 21 June 2011, http://www.genenames.org
This content Based on Australian Institute of Health and Welfare material. Attribution provided as required under the AIHW CC-BY licence.
Related content
Relation | Count |
---|---|
Data Elements implementing this Value Domain | 1 |